Liver in humanized-liver mice: Control vs ortho-toluidine treatment
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE208192
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资源简介：
The gene expression profiling between Control and ortho-toluidine exposure for 4 weeks in liver of NOG-TKm30 female mice transplanted with commercially available human hepatocytes. Female 6- or 7-week-old NOG mice expressing HSVtk mutant clone 30 cDNA under the control of mouse transthyretin gene enhancer/promoter (NOG-TKm30 mice) were transplanted with commercially available human hepatocytes. After 9 or 8 weeks (16-week-old), mice were treated with 0 or 0.6% ortho-toluidine (OTD) for 1 week and 0 or 0.3% OTD for 3 weeks (totally 4 weeks treatment). After treatment, mice were sacrificed, and removed livers. Control and OTD treatment: 2 control female mice, 3 OTD-treated female mice, respectively. Mixed 2 or 3 samples from each group for each RNA-seq.
创建时间：
2023-06-09
