Assessment of gene-gene pair-wise interactions.

The number of significant interactions observed is less than one might expect by chance.P values for gene-gene interactions were obtained between SNPs using likelihood ratio χ2 tests in the logistic regression. Data are presented for those which attained significance at the P1. Significance levels are also presented where terms for potential confounders (collection center, gender, duration of T1D and HbA1c) are included in the adjusted model2.