Expression data from 4T1 cells in low density (LD = 2 mg/mL) or high density (HD = 3.5 mg/mL) collagen gels

The extracellular matrix has been shown to control breast epithelial cell morphogenesis, proliferation and signalling. Here we compared changes in gene expression between 4T1 murine mammary carcinoma cells grown in a low or high density collagen matrix 50,000 4T1 cells were cultured in LD (2 mg/mL) or HD (3.5 mg/mL) collagen gels for 5 days before RNA extraction and hybridization on Affymetrix MTA 1.0 chips