Structure of P. aeruginosa PBP3 in complex with an aryl boronic acid (Compound 2)

Structure of P. aeruginosa PBP3 in complex with an aryl boronic acid (Compound 2) Descriptor: (5-methyl-1H-indazol-6-yl)boronic acid, DIMETHYL SULFOXIDE, GLYCEROL, ... Authors: Newman, H, Bellini, B, Dowson, C.G. Deposit date: 2020-10-30 Release date: 2021-08-11 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.587 Å) Cite: High-Throughput Crystallography Reveals Boron-Containing Inhibitors of a Penicillin-Binding Protein with Di- and Tricovalent Binding Modes. J.Med.Chem., 64, 2021

铜绿假单胞菌青霉素结合蛋白3（PBP3）与芳基硼酸（化合物2）的复合物晶体结构。相关描述组分包括：(5-甲基-1H-吲唑-6-基)硼酸、二甲基亚砜、甘油等。作者为Newman H、Bellini B、Dowson CG。数据提交日期：2020-10-30；发布日期：2021-08-11；最后修改日期：2024-11-20。实验测定方法为X射线衍射（分辨率1.587 Å）。相关引用文献：《高通量晶体学揭示具有双共价与三共价结合模式的青霉素结合蛋白硼酸类抑制剂》，刊载于《药物化学杂志》（J. Med. Chem.）2021年第64卷。