T cell expansion phenotypes (REP, ICM, TAC, CMM, HPLM)
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http://flowrepository.org/id/FR-FCM-Z4TC
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资源简介：
CD3+ T cells from six healthy donor PBMCs (2 separate experiments) were expanded in 5 different conditions (REP,ICM,TAC,CMM,HPLM) for 12 days. T cell phenotype were assessed on day 0 day 12 of expansion by flow Cytometry. Mitochondrial phenotypes were examined in donors L15, L16 and L8. Also assessed the functional impact of switching expansion conditions to CTL:AIM-V medium on Day 11-12.
Conclusion:
T cell phenotypes vary across conditions.
Notes:
We found that REP conditions produce significantly more CD4 T cells from day 0 to day 12 of expansion. REP condition also supported differentiation of TEM, CD137+, PD-1, IFNy and TNFa populations. While the HPLM condition supported increased production of CD25+ populations.
创建时间：
2022-02-01
