Genetic and epigenetic determinants of neurogenesis and myogenesis
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Genetic and epigenetic determinants of neurogenesis and myogenesis
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创建时间：
2012-03-26
相关数据集
miR-17-92 cluster regulates adult hippocampal neurogenesis, anxiety and depression. Mus musculus
Emerging evidence has shown that noncoding RNAs, particularly microRNAs (miRNAs), contribute to the pathogenesis of mood and anxiety disorders, although the molecular mechanisms are poorly understood.
NIAID Data Ecosystem80
Thyroid Hormone Promotes Fetal Neurogenesis [bulk RNA-Seq]
Maternal low thyroxine (T4) serum levels during the first trimester of pregnancy correlate with cerebral cortex volume and mental development of the progeny, but why neural cells during early fetal br
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Gene expression data from human neural stem cells (hNSCs) treated with 10 uM TCQA for 24 hours
TCQA promoted differentiation of hNSCs at least toward the neuronal lineage and suggests the possibility of using TCQA to promote neurogenesis. When differentiation is induced by growth factor withdra
NIAID Data Ecosystem30
A KAP1 phosphorylation switch controls MyoD function during skeletal muscle differentiation (RNA-seq). Mus musculus
The transcriptional activator MyoD serves as a master controller of myogenesis. Often in partnership with Mef2, MyoD binds to the promoters of hundreds of muscle genes in proliferating myoblasts, yet
NIAID Data Ecosystem70
HuR promotes myogenesis by cooperating with YB-1 to modulate the stability of the Myogenin mRNA. HuR promotes myogenesis by cooperating with YB-1 to modulate the stability of the Myogenin mRNA
Our study delineates a novel mechanism for HuR-mediated posttranscriptional regulation of myogenesis that requires its association to YB1 and provides new insights into the central role of posttranscr
NIAID Data Ecosystem40
