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Chlamydial infection-dependent synthesis of sphingomyelin as a novel anti-chlamydial target of ceramide mimetic compounds

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Figshare2022-11-28 更新2026-04-08 收录
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These data are original and unprocessed data performed by Keigo Kumagai. <br> Fig2: Files to show the anti-chlamydial effects of HPA-12-IR and CERT inhibitors are included. Fig3: Two Excel files to calculate the relative ATP level of the drug-treated cells are included. Fig4: Files to show the relative increase of NBD-signal in each inclusion during the incubation are included. Fig5: Files to demonstrate the relative SM synthesis with NBD-ceramide or isotope-labeled serine are included. Fig6: Files to show the anti-chlamydial effects of the drugs in the presence or absence of the serum are included. Fig7: Files to demonstrate the production of PC-HPA-12 by the cidSM-synthesis are included. Fig8: Files to show the chlamydial changes by the treatment with the drugs are included.

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2022-11-28
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