Additional file 1: of Synchronous birth is a dominant pattern in receptor-ligand evolution

Page 1 1: Branch of appearance of each of the 19,928 human genes. 2: Branch of appearance of the 1000 genes of bilaterians drawn randomly. Page 2: Branch of appearance of human genes for the mathematical model. Page 3: Branches of appearance of ligands and receptors. Page 4: List of receptor/ligand interactions. The file contains the interactions present in our database, as well as the interactions present in the list of Ramilowski et al., 2015. Page 5: List of ligands that have evolved rapidly. Page 6: List of characteristics of ligands and receptors used for MCA. The characteristics are the molecular weight before and after cleavage, the synthesis, the groups 1 to 9 according to the characteristics of the proteins (ex glycoproteins), the type of signal and the function of the interaction. (XLSX 578 kb)