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FST and genetic diversity in an island model with background selection

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DataONE2025-08-04 更新2025-08-23 收录
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Background selection, by which selection on deleterious alleles reduces diversity at linked neutral sites, influences patterns of total neutral diversity, πT, and genetic differentiation, FST, in structured populations. The theory of background selection may be split into two regimes: the background selection regime, where selection pressures are strong and mutation rates are sufficiently low such that deleterious alleles are at a deterministic mutation-selection balance, and the interference selection regime, where selection pressures are weak and mutation rates are sufficiently high that deleterious alleles accumulate and interfere with another, leading to selective interference. Previous work has quantified the effects of background selection on πT and FST only for deleterious alleles in the background selection regime. Furthermore, there is evidence to suggest that migration reduces the effects of background selection on FST, but this has not been fully explained. Here, we derive no..., , , # Data from: FST and genetic diversity in an island model with background selection [https://doi.org/10.5061/dryad.p2ngf1w0n](https://doi.org/10.5061/dryad.p2ngf1w0n) ## Description of the data and file structure This data was collected by running simulations in SLiM v3.7.1. The relevant code for the simulations, alongside their subsequent analysis and plotting may be found at [https://github.com/asadrh8/FST-BGS](https://github.com/asadrh8/FST-BGS) ### Files and variables To test background selection theory, we ran simulations of panmictic and structured populations. All data files labelled \"pi_N\" refer to panmictic populations, where the population size is described following an underscore, and all data files labelled \"pi_FST\" contain data from simulations of an island model (a form of structured population). The label \"r\" refers to the per base-pair recombination rate in the simulations from which the data is derived, \"cM\" refers to the map length in centimorgans of the simulate...,
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2025-08-05
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