Pharmacokinetics of single dose vilanterol.

UMEC = umeclidinium; VI = Vilanterol; AUC (0-t) = area under concentration-time curve from time 0 to time of last quantifiable concentration; Cmax = maximum observed plasma concentration; tmax = time of maximum observed plasma concentration; tlast = last time point where the concentration is above the limit of quantification, CI = confidence interval; NC = not calculated.aSummary statistics derived following Cmax imputation with ½ LLQ (15 pg/mL) and AUC imputation with ½ lowest observed value for the parameter across treatments;*Data from one subject is imputed.bUMEC/VI vs VI ratio analysis done without imputing the NQ results.cPresented as geometric mean and 95% CI.dPresented as median and range.