Oncolytic virotherapy mediated anti-tumor response in primary cutaneous B-cell lymphoma: a single-cell perspective

We analyzed fine-needle aspirate (FNA) samples of T-VEC-treated primary cutaneous B-cell lymphoma patients. FNAs were taken from injected and non-injected lesions before and at several time points after the patient's first injection. The study aimed to describe the dynamics of the viral infection, characterize the changes in the tumor microenvironment caused by T-VEC-treatment compare injected and non-injected lesions and identify the mechanism of action.EGA study EGAS00001004904