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Finite Mixtures of Multivariate Contaminated Normal Censored Regression Models

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NIAID Data Ecosystem2026-05-02 收录
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https://figshare.com/articles/dataset/Finite_Mixtures_of_Multivariate_Contaminated_Normal_Censored_Regression_Models/29039883
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The complexity of model-based clustering grows as outliers become more prevalent, compounded by restrictions imposed by the detection of quantification. This article introduces a finite mixture of multivariate contaminated normal (FM-MCN) distributions tailored for handling censored data, referred to as the FM-MCNC model henceforth. Subsequently, the FM-MCNC model is extended to tackle the multivariate linear regression issue, leading to the formulation of the FM-MCN censored regression (FM-MCNCR) model. For the estimation of model parameters, we devise a computationally analytical alternating expectation conditional maximization (AECM) algorithm. Additionally, we present an information matrix-based formula to approximate the asymptotic standard errors of parameter estimates. Importantly, the AECM algorithm serves a dual role by not only facilitating parameter estimation but also providing methods to recover censored measurements and detect outlier data points as a by-product when it converges. The efficacy and advantages of the proposed methodology are illustrated through a series of simulations and two real-life data examples. Supplemental data for this article can be accessed here.
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2025-05-12
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