Unveiling the Impact of ApoF Deficiency on Liver and Lipid Metabolism: Insights from Transcriptome-Wide m6A Methylome Analysis in Mice

The transcriptome-wide MeRIP sequencing in the ApoF KO mice has demonstrated the role of this crucial apolipoprotein in the liver health and the lipid metabolism. Overall design: The aim of the present study was to elucidate the change of m6A methylome in the lipid metabolism disorder mice with ApoF gene knockout, based on the bioinformatics methods of transcriptome-wide m6A methylome epitranscriptomics.