Overlapping representations of food and social stimuli in VTA dopamine neurons

2-photon imaging and behavioral data accompanying publication of \"Overlapping representations of food and social stimuli in VTA dopamine neurons\" (Lindsay Willmore, Adelaide Minerva, Ben Engelhard, Brenna McMannon, Nirja Oak, Stephan Thiberge, Malavika Murugan, Catherine Jensen Pena, Ilana Witten). This dataset contains all information required to recreate figures from the paper. , Transgenic mice expressing the calcium-sensitive fluorescent indicator GCamp6f in dopamine neurons were used to perform 2-photon calcium imaging of ventral tegmental area as mice were presented with various social and food stimuli. See paper for detailed paradigm methods. Regions of interest (ROIs) containing putative single neurons were extracted using suite2p. Contents of this dataset include: 2p_aligned: aligned time traces for imaging ROIs & neuropil; syncing signals for behavior analysis 2p_ops: output ROIs and statistics from suite2p for each imaging session body: DeepLabCut tracking files for points on the body of the imaged and stimulus mice for each relevant imaging session pupil: DeepLabCut tracking files for points on the pupil of the imaged mouse for each relevant imaging session tongue: tracking of if the tongue was seen as a proxy for licking for each relevant imaging session usv: syllable_sequence files from MUPET across sessions, usv_count summary syllable count da...,本数据集配套于论文《腹侧被盖区多巴胺神经元对食物与社交刺激的重叠表征》（*Overlapping representations of food and social stimuli in VTA dopamine neurons*，作者Lindsay Willmore、Adelaide Minerva、Ben Engelhard、Brenna McMannon、Nirja Oak、Stephan Thiberge、Malavika Murugan、Catherine Jensen Pena、Ilana Witten）的发表，包含复现该论文所有图表所需的全部数据。本研究使用在多巴胺神经元中表达钙敏感荧光指示剂GCamp6f的转基因小鼠，在小鼠暴露于各类社交与食物刺激时，对其腹侧被盖区（ventral tegmental area, VTA）开展双光子钙成像（2-photon calcium imaging）。详细的实验范式与方法参见原论文。使用suite2p软件提取包含疑似单个神经元的感兴趣区域（Regions of Interest, ROIs）。本数据集包含以下内容： - `2p_aligned`：成像感兴趣区域与神经纤维丛（neuropil）的对齐时间序列，以及用于行为分析的同步信号 - `2p_ops`：各成像会话中suite2p输出的感兴趣区域与统计结果 - `body`：各相关成像会话中，成像小鼠与刺激小鼠身体部位的DeepLabCut追踪文件 - `pupil`：各相关成像会话中，成像小鼠瞳孔部位的DeepLabCut追踪文件 - `tongue`：各相关成像会话中，以舌部可见情况作为舔舐代理指标的追踪数据 - `usv`：多会话下来自MUPET的音节序列文件，以及usv_count音节计数汇总数据……