Equine metabolic syndrome in Colombian creole horse: case report

ABSTRACT The equine metabolic syndrome is a condition that can be recognized because of obesity, insulin resistance and laminitis. Genetic factors could play a role in the occurrence of this syndrome. Certain breeds such as ponies (including the South American creole horses) have a lower sensibility to insulin and a higher prevalence of hyperinsulinemia. The environment and management conditions, such as overfeeding and lack of exercise are factors that bring a propensity for obesity. The adipose tissue works as an endocrine organ producing hormones (adipokines or adipocytokines) that affect the horse´s metabolism. The objective of this report is to describe the first case report of a Colombian creole mare with a metabolic syndrome, diagnosed by means of the combined test of glucose-insulin and clinical signs. Early diagnosis of this entity and an adequate treatment are useful for improving the life and the zootechnical conditions of the patient.摘要：马代谢综合征（equine metabolic syndrome）是一类可通过肥胖、胰岛素抵抗（insulin resistance）及蹄叶炎进行识别的疾病。遗传因素可能在该综合征的发生中发挥一定作用。部分品种（如矮马，包含南美克里奥尔马）对胰岛素的敏感性更低，且高胰岛素血症（hyperinsulinemia）的患病率更高。环境与饲养管理条件，如过度饲喂、缺乏运动等，是增加肥胖易感性的相关影响因素。脂肪组织作为内分泌器官，可分泌影响马匹代谢的激素——脂肪因子（adipokines，又称adipocytokines）。本报告旨在描述首例哥伦比亚克里奥尔母马罹患马代谢综合征的病例，该病例通过葡萄糖-胰岛素联合检测结合临床症状得以确诊。对该疾病的早期诊断与合理治疗，有助于改善患马的生存质量与畜牧生产性能。