Vaccine evaluation with India Rhesus model

NIAID Data Ecosystem2026-05-26 收录

疫苗免疫应答

B细胞受体

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP168514 数据链接链接失效反馈

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资源简介：

This project includes 15 India Rhesus monkey, and total 75 samples (Each individual includes five timepoints). Full-length Heavy chain of B cells were amplified and sequenced by Miseq.

创建时间：

2018-12-25

Peyer’s Patch Germinal Centers Select Innate-like BCRs

B细胞受体

肠道免疫

Primary B cell receptor (BCR)/antibody variable region exons are generated by V(D)J recombination with junctional diversification creating immensely diverse antigen contact-encoding CDR3s. While most

NIAID Data Ecosystem160

Transcriptional profiling of HBV-naïve subjects before vaccination against Hepatitis A/B viruses, Diphtheria/Tetanus toxoids and Cholera.

疫苗免疫应答

免疫衰老

Mechanisms of poor responses to vaccines remain unknown. Hepatitis B virus-naïve elderly subjects received three vaccines, including a vaccine against hepatitis B virus (HBV). Pre-vaccination high dim

NIAID Data Ecosystem20

IGH VDJ-RNA-seq of circulating plasma cells at day zero and seven relative to experimental vaccination dosing

疫苗免疫监测

B细胞受体

IGH VDJ-RNA-sequencing of CD19+IgD-CD27+CD71+CD38+CD20- circulating plasma cells prior to vaccination (day 0) and seven (day 63) days after the third vaccination. Overall design: Blood samples were ta

NIAID Data Ecosystem00

Cellular response to Vi-vaccination

疫苗免疫应答

细胞免疫反应

To investigate the cellular response in peripheral blood following parenteral vaccination with either Vi-TT or Vi-PS. https://doi.org/10.3389/fimmu.2020.574057

NIAID Data Ecosystem70

Production by activated human T cells of interleukin 4 but not interferon-gamma is associated with elevated levels of serum antibodies to activating malaria antigens.

疫苗免疫应答

T细胞功能分析

T cells play a crucial role in antibody-mediated and antibody-independent immunity against Plasmodium falciparum malaria. Therefore, a vaccine immunogen should include parasite-derived B- and T-cell e

PubMed Central00

Vaccine evaluation with India Rhesus model

资源简介：

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