Multivariate Cox proportional hazards model of each SNP associated with the occurrence of hip fracture.

All analyses were adjusted for independent non-genetic factors: age, body mass index, Japanese version of Health Assessment Questionnaire disability score, and history of total knee replacement. [7]. *Alleles are listed as major allele/minor allele. SNP, single nucleotide polymorphism; MAF, minor allele frequency; HR, hazard ratio; CI, confidence interval; OPG, osteoprotegerin; ZBTB40, zinc finger and BTB domain containing 40; MHC, major histocompatibility complex; RANK, receptor activator of the nuclear factor-κB; SPTBN1, spectrin β nonerythrocytic 1; LRP4, low-density lipoprotein receptor-related protein 4.