Cryo-EM structure of bsAb3 Fab-Gn-Gc complex

Cryo-EM structure of bsAb3 Fab-Gn-Gc complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein C, Glycoprotein N, ... Authors: Wu, Y, Sun, J.Q. Deposit date: 2023-10-12 Release date: 2024-06-12 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.27 Å) Cite: Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model. Proc.Natl.Acad.Sci.USA, 121, 2024bsAb3 Fab-Gn-Gc复合物的冷冻电镜（Cryo-EM）结构 描述项：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、糖蛋白C（Glycoprotein C）、糖蛋白N（Glycoprotein N）…… 作者：Wu, Y、Sun, J.Q. 提交日期：2023-10-12 发布日期：2024-06-12 最后修改日期：2025-07-02 检测方法：电子显微镜（3.27 Å） 引用文献：靶向发热伴血小板减少综合征病毒（SFTSV）两种糖蛋白的双特异性抗体在小鼠模型中展现协同中和与保护作用。Proc.Natl.Acad.Sci.USA, 121, 2024