Nucleosome profiles in strains with different numbers of nucleosomes at HML and HMR

We report nucleosome positions by using native Mnase-seq. The results strongly suggest that nucleosome positions don't change at the heterochromatic locus HMR upon removal of adjacent nucleosomes via deletion of nucleosomal DNA. Positions of nucleosomes at HML are also quantified. Overall design: Genome-wide analysis of nucleosome positions in strains of interest, with a particular focus on nucleosome positioning at HML and HMR.