Biological Data Bus v7 — Multi-protocol neural communication framework & Cardiac Gating of the Biological Data Bus: Heart Phase Modulates Temporal→Insula Communication in Human iEEG

Contact-level iEEG analysis of inter-regional brain communication protocols using COGITATE consortium data (n=38 subjects, 2048 Hz). Key findings:- The gamma/high-gamma power ratio (30-80 Hz / 80-150 Hz) is the dominant predictor of inter-regional coupling, encoding the direction of information flow between brain regions.- Each neural pathway uses a distinct signaling protocol: visual cortex communicates via amplitude modulation (slow, tonic), amygdala uses high-gamma bursts (fast, prioritized), temporal lobe (memory) uses gamma/high-gamma ratio (strongest coupling: rho=0.775).- The temporal-to-insula bus (rho=0.775) is three times stronger than the visual-to-insula bus (rho=0.297). The insula prioritizes what you RECOGNIZE over what you SEE. Biologically, the insula regulates the body (heart rate, visceral responses). It does not need to know you see "orange pixels" it needs to know you see "fire" to accelerate your heart. The temporal lobe translates pixels into meaning, which is why its direct line to the insula is three times stronger.- Competitive inhibition: amygdala activation suppresses insular response (rho=-0.293, 399/528 contact pairs significant).- Phase 5 Recovery targeted spectral analysis recovers coupling values up to rho=0.713 that region-averaged approaches dilute. Contains: analysis code (Python), 3D interactive simulator (HTML/Three.js), per-subject results (JSON), group report, synthesis schema (PDF), electrode mappings. Data source: COGITATE iEEG dataset (Melloni et al., 2024, Max Planck Institute). DOI: 10.17617/1.6qpg-gz82 Work in progress. Preliminary results on 6/38 subjects.