Acyl chain remodelling of PI

In the acyl chain remodelling pathway (Lands cycle), phosphatidylinositol (PI) is hydrolyzed by phospholipases and subsequently reacylated by acyltransferases. These cycles modify the fatty acid composition of glycerophospholipids to generate diverse molecules asymmetrically distributed in the cell membrane (Ghomashchi et al. 2010, Singer et al. 2002, Gijon et al. 2008, Lee et al. 2008).

在酰基链重塑途径（Lands 循环）中，磷脂酰肌醇（PI）被磷脂酶水解，随后由酰基转移酶进行再酰基化。此循环过程可调节甘油磷脂的脂肪酸组成，从而生成在细胞膜中非对称分布的多种分子（Ghomashchi 等，2010 年，Singer 等，2002 年，Gijon 等，2008 年，Lee 等，2008 年）。