Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by (A611V, F608S) mutations at 1.55A

Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by (A611V, F608S) mutations at 1.55A Descriptor: DEXAMETHASONE, GLYCEROL, Glucocorticoid receptor, ... Authors: Schoch, G.A, Seitz, T, Benz, J, Banner, D, Stihle, M, D'Arcy, B, Thoma, R, Sterner, R, Hennig, M, Ruf, A. Deposit date: 2010-04-22 Release date: 2010-09-15 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening. J.Mol.Biol., 403, 2010

分辨率为1.55埃的、经(A611V, F608S)突变稳定的小鼠糖皮质激素受体（glucocorticoid receptor）激动剂构象晶体结构。描述符：地塞米松（DEXAMETHASONE）、甘油（GLYCEROL）、糖皮质激素受体……。作者：Schoch, G.A.、Seitz, T.、Benz, J.、Banner, D.、Stihle, M.、D'Arcy, B.、Thoma, R.、Sterner, R.、Hennig, M.、Ruf, A.。存档日期：2010-04-22；发布日期：2010-09-15；最后修改日期：2023-09-06。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.55埃。引用文献：通过高通量文库筛选提升糖皮质激素受体配体结合域的稳定性与可溶性，发表于《J.Mol.Biol.》，2010年，第403卷。