Whole-blood transcriptomic profiling highlights rituximab response in rheumatoid arthritis
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE54629
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Objective: We performed whole-blood transcriptomic profiling for patients with rheumatoid arthritis (RA) who received rituximab (RTX). We aimed to identify a molecular signature that could predict the clinical response to RTX and transcriptomic changes after RTX therapy. Methods: We performed a microarray assay of the whole human genome with RNA from a peripheral blood sample taken before the first RTX cycle from 68 patients included in the SMART study (24 EULAR non-responders and 44 responders at week 24). The transcriptomic profile was also assessed 24 weeks after the first RTX administration
创建时间：
2018-07-26
