Spearman rank correlation analysis for pairs of E-cadherin turnover rates.

E-cadherin turnover rates were measured by FRAP as follows: iterative pairs were obtained by measuring E-cadherin turnover rates in a same spot at two time points 45 minutes apart (line 1). Single-cell pairs were obtained by measuring rates simultaneously at two distinct junctions of a same cell (line 2). Single-junction pairs were assessed by dual-color FRAP on E-cadherin from two neighbor cells in a same junction (line 3). Correlations within pairs (between koff#2 and koff#1) were estimated by computing the Spearman coefficient symsymρ. As a comparison to evaluate the strength of the correlation, this result is compared to a randomized situation, obtained by a random permutation within one set of rates (koff#2). Significant correlations (p<0.05) are shown in boldface.
Spearman rank correlation analysis for pairs of E-cadherin turnover rates.