Additional file 2 of De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity

Table S1. Association of clinical variables with PC1 and the liver score of CRLMs. Table S2. Genes (n = 514) used as input for NMF classification of CRLMs. Table S3. GSEA results based on NMF classification at K = 2. Table S4. GSEA result for the de novo LMS groups (at NMF K = 5). Table S5. Associations of the LMS subtypes (grouped) with mutations and selected clinical variables. Table S6: Associations of the LMS groups with clinical variables. Table S72. Univariable Cox Proportional hazard analysis. Table S8. Multivariable Cox Proportional hazard analysis. Table S9. Clinical information of GSE131418 dataset according to LMS subtypes. Table S10. Predictive RF model specification.