Genes having differential expression either between strains or among different embryonic days.
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Expression assay by NanoString nCounter. 3 RNA samples of pia at each time point for each strain, with each sample composing of ≥8 embryos from ≥2 litters (18 samples, ∼200 embryos). Transcript number for each gene normalized to mean transcript number for 6 housekeeping genes: βactin, Gapdh, Tubb5, Hprt1, Ppia, Tbp.*Gene number same as in Figure 6 and Table S2.†I, genes in EMMA region; II, genes in 95% CI of Chr 7 QTL; III, angiogenic-related genes located elsewhere in genome; IV, proliferation-related genes located elsewhere in genome.‡Fold change for Bc vs B6 if positive and B6 vs Bc if negative.§Bonferroni-adjusted p values (p-value÷150, for 150 genes/splice forms assayed) from 2-way ANOVA for 2 strains (20 genes p
创建时间：
2015-12-02
