Epigenetic differences in genetically identical Arabidopsis thaliana plants modulate alternative splicing

In plants, co-transcriptional regulation of AS in plants has been recently reported. However, how dynamic changes in the chromatin influence the AS process upon cold stress remains poorly understood. The aim of this study is to understand how epigenetic features (i.e: Nucleosome occupancy and DNA methylation) alone without the confounding effects of sequence variation affect gene expression and alternative splicing profiles under normal (22°C) and cold stress (4°C) in Arabidopsis thaliana.