Genome-wide targets of conserved histone chaperone Asf1 in budding yeast

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Asf1, through its histone chaperone activity, helps chromatin closing/opening during DNA replication, repair, recombination and transcription

Asf1（ASF1）凭借其组蛋白伴侣活性，可在DNA复制、DNA修复、DNA重组及基因转录过程中辅助染色质的闭合与开放。