Crystal structure of the SARS-CoV-2 (COVID-19) main protease (Mpro) in complex with inhibitor Jun89-3-C1

Crystal structure of the SARS-CoV-2 (COVID-19) main protease (Mpro) in complex with inhibitor Jun89-3-C1 Descriptor: 3C-like proteinase nsp5, N-([1,1'-biphenyl]-4-yl)-2-chloro-N-[(1R)-2-oxo-2-{[(1S)-1-phenylethyl]amino}-1-(pyridin-3-yl)ethyl]acetamide Authors: Lewandowski, E.M, Butler, S.G, Hu, Y, Tan, H, Wang, J, Chen, Y. Deposit date: 2023-01-12 Release date: 2024-01-17 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Crystal structure of the SARS-CoV-2 (COVID-19) main protease (Mpro) in complex with inhibitor Jun89-3-C1 To Be Published

SARS-CoV-2（新型冠状病毒COVID-19）主蛋白酶（main protease, Mpro）与抑制剂Jun89-3-C1结合的晶体结构。描述：3C样蛋白酶nsp5，配体为N-([1,1'-联苯基]-4-基)-2-氯-N-[(1R)-2-氧代-2-{[(1S)-1-苯乙基]氨基}-1-(吡啶-3-基)乙基]乙酰胺。作者：Lewandowski E.M.、Butler S.G.、Hu Y.、Tan H.、Wang J.、Chen Y.。提交日期：2023-01-12；发布日期：2024-01-17；最后修改日期：2024-11-13。实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率2.08 Å）。引用信息：SARS-CoV-2（COVID-19新型冠状病毒）主蛋白酶（Mpro）与抑制剂Jun89-3-C1结合的晶体结构，待发表。