Cryo-EM structure of minimal TRPV1 with 2 bound RTX in adjacent pockets
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Cryo-EM structure of minimal TRPV1 with 2 bound RTX in adjacent pockets Descriptor: (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ... Authors: Zhang, K, Julius, D, Cheng, Y. Deposit date: 2021-05-24 Release date: 2021-09-22 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (3.46 Å) Cite: Structural snapshots of TRPV1 reveal mechanism of polymodal functionality. Cell, 184, 2021
结合2个RTX配体于相邻口袋的最小化TRPV1冷冻电镜结构
描述物:(2S)-1-(丁酰氧基)-3-{[(R)-羟基{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-五羟基环己基]氧基}磷酰基]氧基}丙-2-基十三烷酸酯、钠离子、瞬时受体电位阳离子通道V亚家族成员1(Transient receptor potential cation channel subfamily V member 1)……
作者:Zhang K, Julius D, Cheng Y
提交日期:2021-05-24
发布日期:2021-09-22
最后修改日期:2024-11-20
实验方法:电子显微镜(3.46埃)
引用文献:《TRPV1的结构快照揭示其多模态功能机制》,《细胞》(Cell),184卷,2021年
创建时间:
2021-05-24



