BIOGRID CURATED DATA FOR HEM12 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for HEM12 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Uroporphyrinogen decarboxylase; catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; a hem12 mutant has phenotypes similar to patients with porphyria cutanea tarda

蛋白质-蛋白质、遗传和化学相互作用数据集，针对酿酒酵母（Saccharomyces cerevisiae S288c）中的HEM12基因，由BioGRID（https://thebiogrid.org）精心整理；定义：尿卟啉原脱羧酶；催化血红素生物合成途径中的第五步；定位于细胞质和细胞核；hem12突变体的表型与晚期皮肤卟啉病患者相似。