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Competition between pre-mRNAs for a limiting splicing machinery drives global changes in splicing

Alliance of Genome Resources2026-08-01 收录

剪接竞争机制

剪接效率调控

数据链接：

https://www.yeastgenome.org/dataset/GSE44219 数据链接链接失效反馈

官方服务：

资源简介：

During meiosis in yeast, global splicing efficiency increases

在酵母（yeast）的减数分裂（meiosis）过程中，全局剪接效率升高

应用场景：

剪接效率调控

内含子进化适应

mRNA splicing is a key process in eukaryotic gene expression. Most Intron-containing genes are constitutively spliced, and hence must undergo splicing to produce a functional mRNA. Therefore, regulati

NIAID Data Ecosystem40

Human U2 snRNA BSL sequence mediates splicing efficiency driven by branchpoint sequence complementarity

U2snRNA功能

剪接效率调控

To investigate the global effects of perturbing U2 snRNA sequence on splicing and gene expression, we carried out transcriptomic analysis of HEK293T cell lines stably expressing U2 snRNA mutants C28U

NIAID Data Ecosystem10

Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency [ARTR-seq]

核斑点RNA定位

剪接效率调控

Nuclear speckles, a type of membraneless nuclear organelle in higher eukaryotic cells, play a vital role in gene expression regulation. Using the reverse transcription-based RBP binding sites sequenci

NIAID Data Ecosystem00

[E-MTAB-5] Dynamic repertoire of a eukaryotic transcriptome surveyed at single nucleotide resolution

真核转录组动态分析

剪接效率调控

Recent data from several organisms indicate that the transcribed portions of genomes are larger and more complex than expected, and many functional properties of transcripts are not based on coding se

NIAID Data Ecosystem20

Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency [ARTR-seq]. Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency [ARTR-seq]

RNA定位

剪接效率调控

NIAID Data Ecosystem00