Altering translation allows E. coli to overcome chemically stabilized G-quadruplexes
收藏DataCite Commons2025-11-19 更新2026-04-25 收录
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https://www.osti.gov/servlets/purl/3001667
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资源简介：
To investigate the effects of stabilizing G-quadruplexes on Escherichia coli, cells were grown in the presence of the G-quadruplex stabilizing compound, NMM, and RNA-seq was performed. This was done for the control cell strain (MG1655 dtolC) as well as a strain with a decrease in a translation elongation factor (MG1655 dtolC tufA::kan). TPM values were used for differential gene expression analysis between each growth condition. All samples were grown and sequenced in triplicate.
提供机构：
Great Lakes Bioenergy Research Center (GLBRC), Madison, WI (United States)
创建时间：
2025-11-17
