The human protein-coding gene ILRUN (inflammation and lipid regulator with UBA-like and NBR1-like domain, previously C6orf106) is a recently-characterised inhibitor of the transcription regulators p30
The IBTK gene encodes the major protein isoform IBtkα, that was recently characterized as substrate receptor of Cul3-dependent E3 ligase, regulating ubiquitination coupled to proteasomal degradation o
Log IC50 values for inhibition of nicotinic responses in CN21 and SH-SY5Y cells by the test compounds. Data show mean ± SEM. All values were obtained by best-fit of the Hill-equation as described in t
