T-dependent induction of natural IgM-producing B-1 plasma cells expressing a unique repertoire

NIAID Data Ecosystem2026-03-13 收录

B细胞免疫缺陷

适应性免疫受体库

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA781755 数据链接链接失效反馈

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B and plasma cells were sorted from mouse bone marrow and sequenced via AIRR-seq

创建时间：

2021-11-19

Supplementary Material for: Postnatal and Adult Immunoglobulin Repertoires of Innate-Like CD19 + CD45R lo B Cells

B细胞免疫缺陷

抗体库分析

The diversity in antibody repertoire relies on different B cell populations working efficiently to fulfil distinct specific functions. We recently described an innate-like CD19+CD45R-/lo (19+45Rlo) ce

NIAID Data Ecosystem150

ZBTB38 is dispensable for hematopoiesis and antibody responses.. ZBTB38 is dispensable for hematopoiesis and antibody responses.

B细胞免疫缺陷

基因功能研究

We performed RNA-sequencing of ZBTB38-sufficient and -deficient germinal center B cells. Very few genes were dysregulated by the absence of ZBTB38. Overall design: RNA-seq of ZBTB38 KO and WT germinal

NIAID Data Ecosystem40

Transcriptomics of the immune response to Schistosomiasis. Transcriptomics of the immune response to Schistosomiasis

血吸虫病免疫转录组

适应性免疫受体库

This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria)

NIAID Data Ecosystem20

Loss of TET2 results in DNA methylation changes in mouse GC B-cells (hMeDIP-Seq data set)

表观遗传调控

B细胞免疫缺陷

Absence of Tet2 at mouse cells results in loss of hydroxymethylcytosine Hydroxymethylmethylcytosine DNA immunoprecipitation sequencing (hMeDIP-seq) of mouse TET2 WT and KO GC B-cells

NIAID Data Ecosystem80

Impaired B-cell function in ERCC2 deficiency

B细胞免疫缺陷

基因变异与免疫反应

Trichothiodystrophy-1 (TTD1) is an autosomal-recessive disease and caused by mutations in ERCC2, a gene coding for a subunit of the TFIIH transcription and nucleotide-excision repair (NER) factor. In

NIAID Data Ecosystem30

T-dependent induction of natural IgM-producing B-1 plasma cells expressing a unique repertoire

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