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Prothrombotic Hemostasis Disturbances in Patients with Severe COVID-19

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NIAID Data Ecosystem2026-03-12 收录
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The aim of this prospective observational study was to describe the longitudinal changes in hemostasis parameters assessed daily in 21 COVID-19 patients during their intensive care unit (ICU) stay. Our main findings were that (i) daily standard measurements consistent with a prothrombotic state persisted over the first days and improved thereafter, but did not normalize in all patients; (ii) increased thrombin potential (hypercoagulability) and decreased fibrinolysis were frequent and (iii) a high inter-patient variability was observed.
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2020-10-15
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