Simple and Rapid Synthesis of Branched Peptides through Microwave-Assisted On-Bead Ligation
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https://figshare.com/articles/dataset/Simple_and_Rapid_Synthesis_of_Branched_Peptides_through_Microwave-Assisted_On-Bead_Ligation/16859708
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资源简介:
A rapid on-bead convergent method
for preparing branched peptides
was reported. Linear peptides were prepared on Dbz resin and ligated
various branched cores, including lysine dendrons and other dendritic
compounds. Alongside microwave irradiation, <1.5 equiv of peptides
is sufficient to afford 50–65% yields of pure branched peptides
without chromatographic purification. Remarkably, the desired compounds
were prepared within hours.
创建时间:
2021-10-22



