BACKGROUND/ AIMS: Severe forms of alcoholic liver disease are associated with increased susceptibility to infections largely due to immune dysfunction. In this study, we analyze the phenotypic, molecu

NIAID Data Ecosystem10

DNMT3A Reads and Connects Histone H3K36me2 to DNA methylation [RNA-seq]

表观遗传调控

甲基化反应机制

DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon

NIAID Data Ecosystem00

Table_5_Molecular mechanisms governing the progression of nephritis in lupus prone mice and human lupus patients.xlsx

狼疮肾炎进展机制

基因表达谱分析

IntroductionPathologic inflammation is a major driver of kidney damage in lupus nephritis (LN), but the immune mechanisms of disease progression and risk factors for end organ damage are poorly unders

NIAID Data Ecosystem30

Hepatic tissue expression profiles of Acsm3 knockout and control mice.

代谢机制研究

基因表达谱分析

Acyl-CoA synthetase medium-chain family member 3 (ACSM3) is one member of ACSM family and localized on the outer membrane of mitochondria, which catalyzes the activation of medium-chain (C4-C14) lengt

Alliance of Genome Resources00

Gene expresion changes following knockdown of KDM4C in primary fibroblasts

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