Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound 5 at 1.57A resolution
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Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound 5 at 1.57A resolution Descriptor: 3-[1-[4-(methylaminomethyl)phenyl]piperidin-4-yl]-1-pyrrolidin-1-yl-propan-1-one, EthR Authors: Surade, S, Blaszczyk, M, Nikiforov, P.O, Abell, C, Blundell, T.L. Deposit date: 2015-11-25 Release date: 2016-02-03 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.57 Å) Cite: A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters. Org.Biomol.Chem., 14, 2016
分辨率1.57埃的结核分枝杆菌（Mycobacterium tuberculosis）转录调控阻遏蛋白（Transcriptional Regulatory Repressor Protein）EthR与化合物5复合物的晶体结构
配体描述：3-[1-[4-(甲氨基甲基)苯基]哌啶-4-基]-1-吡咯烷-1-基-丙-1-酮，EthR
作者：Surade S、Blaszczyk M、Nikiforov P.O、Abell C、Blundell T.L.
提交日期：2015-11-25
发布日期：2016-02-03
最后修改日期：2024-01-10
实验方法：X射线衍射（1.57 Å）
引用文献：通过片段融合策略开发可作为乙硫酰胺增效剂的结核分枝杆菌EthR小分子抑制剂. Org.Biomol.Chem., 14, 2016
创建时间：
2015-11-25
