Simulated ancient metagenomic ground truth dataset used for aMeta publication

This is a simulated ancient metagenomic dataset used for benchmarking the anciemt microbiome profiling workflow aMeta against Heuristic Operations for Pathogen Screening (HOPS), see link under references. The dataset was simulated using gargammel software, see link under references. Both ancient and modern reads were simulated, sequencing errors and Illumina adapters were added. The simulated datase was built by Nikolay Oskolkov, Lund University, Sweden, within the NBIS SciLifeLab long-term support project, PI Anders Götherström, Centre for Palaeogenetics, Stockholm, Sweden.

本数据集为一模拟的古微生物组数据集，旨在对古微生物组分析流程aMeta与病原体筛选启发式操作（HOPS）进行基准测试。该数据集采用gargammel软件进行模拟，具体链接见参考文献部分。模拟数据集包括古代和现代的序列读取，并添加了测序错误和Illumina适配器。该模拟数据集由瑞典隆德大学的Nikolay Oskolkov构建，其研究项目得到NBIS SciLifeLab长期支持项目资助，项目负责人为Anders Götherström教授，研究地点位于瑞典斯德哥尔摩的古代遗传学中心。