Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the arginine-bound inward-occluded state

Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the arginine-bound inward-occluded state Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARGININE, ... Authors: Ye, M, Zhou, D, Pike, A.C.W, Wang, S, Wang, D, Bakshi, S, Brooke, L, Williams, E, Elkins, J, Stuart, D.I, Sauer, D.B. Deposit date: 2024-06-17 Release date: 2025-07-02 Last modified: 2026-04-08 Method: ELECTRON MICROSCOPY (2.79 Å) Cite: Amino acid and viral binding by the high-affinity Cationic Amino acid Transporter 1 (CAT1) from Mus musculus. Nat Commun, 17, 2026结合FrMLV受体结合域（FrMLV-RBD）且处于精氨酸结合内向封闭构象的小家鼠阳离子氨基酸转运蛋白1（MmCAT1）冷冻电镜结构 描述项：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、精氨酸（ARGININE）等 作者：Ye, M、Zhou, D、Pike, A.C.W、Wang, S、Wang, D、Bakshi, S、Brooke, L、Williams, E、Elkins, J、Stuart, D.I、Sauer, D.B 提交日期：2024-06-17 发布日期：2025-07-02 最后修改日期：2026-04-08 实验方法：电子显微镜（分辨率2.79埃） 引用文献：《小家鼠来源的高亲和力阳离子氨基酸转运蛋白1（CAT1）的氨基酸结合与病毒结合特性》，Nat Commun，第17卷，2026年