X-ray structure of the complex between human alpha thrombin and a modified thrombin binding aptamer (mTBA)

X-ray structure of the complex between human alpha thrombin and a modified thrombin binding aptamer (mTBA) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, ... Authors: Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. Deposit date: 2011-02-03 Release date: 2011-10-19 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Thrombin-aptamer recognition: a revealed ambiguity. Nucleic Acids Res., 39, 2011

人源α凝血酶（human alpha thrombin）与修饰型凝血酶结合适配体（modified thrombin binding aptamer, mTBA）复合物的X射线晶体结构。配体描述：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖（2-acetamido-2-deoxy-beta-D-glucopyranose）、D-苯丙酰基-N-[(2S,3S)-6-{[氨基(亚氨基)甲基]氨基}-1-氯-2-羟基己-3-基]-L-脯氨酰胺、钾离子（POTASSIUM ION）等。作者：Russo Krauss I、Merlino A、Mazzarella L、Sica F。提交日期：2011-02-03；发布日期：2011-10-19；末次修改日期：2024-11-06。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.14埃（Å）。引用文献：《凝血酶-适配体识别：一项被揭示的模糊性》（Thrombin-aptamer recognition: a revealed ambiguity），《核酸研究》（Nucleic Acids Res.），第39卷，2011年。