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Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-glucose (conformation 2)

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Protein Data Bank Japan2024-10-09 更新2026-04-19 收录
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Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-glucose (conformation 2) Descriptor: 1,3-PROPANDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Roversi, P, Zitzmann, N, Bayo, Y, Le Cornu, J.D. Deposit date: 2022-04-06 Release date: 2022-04-20 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.89 Å) Cite: A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint To Be Published

来自嗜热毛壳菌(Chaetomium thermophilum)的UDP-葡萄糖糖蛋白葡萄糖基转移酶(UDP-Glucose Glycoprotein Glucosyltransferase)催化结构域,与UDP-葡萄糖(UDP-glucose)形成构象2的复合物。 配体描述:1,3-丙二醇、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、钙离子…… 作者:Roversi, P、Zitzmann, N、Bayo, Y、Le Cornu, J.D. 存档日期:2022-04-06 发布日期:2022-04-20 最后修改日期:2024-10-09 实验方法:X射线衍射(分辨率1.89 Å) 引用文献:《UGGT的8-羟基喹啉亚毫摩尔级抑制剂:内质网糖蛋白质量质控检查点》,待发表
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2022-04-06
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