Multiple interspecies recombination events documented by whole genome sequencing in multidrug resistant Haemophilus influenzae clinical isolates

Haemophilus influenzae was long known as an easy-to-treat bacterium but the rise of resistance against beta-lactams and other critically important antibiotics is now an increasing concern. We describe here the whole genome sequencing analysis of three non typeable H. influenzae isolates received in 2018 and 2019 by the Belgian National Reference Centre for Hi as they presented an unusual multi-resistant profile.