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Transcriptome profiles of antibody-producing CHO cells across different amplification strategies

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https://www.ncbi.nlm.nih.gov/sra/SRP212617
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The mechanism of action behind the increased secretion capacity of the amplified progeny of CHO cells is investigated in this study through comparative transcriptomic analysis Overall design: The amplified DG-44 CHO cells, taken at both exponential and stationary growth phase were compared to non-amplified CHO DG-44 cells. Non-producing CHO-S samples were used as negative controls.
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2020-06-30
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