Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 0.1 millimolar EDTA, and at pH 8.0

Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 0.1 millimolar EDTA, and at pH 8.0 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... Authors: Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. Deposit date: 2018-10-01 Release date: 2018-11-28 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (6.88 Å) Cite: Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018

处于“2-Knuckle-Symmetric”构象的异二聚体N-甲基-D-天冬氨酸（NMDA）受体GluN1/GluN2A，该复合物与甘氨酸、谷氨酸结合，反应体系含0.1毫摩尔乙二胺四乙酸（EDTA），且pH值为8.0。描述项：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1-4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、离子型谷氨酸受体……作者：Jalali-Yazdi, F、Chowdhury, S、Yoshioka, C、Gouaux, E。存档日期：2018-10-01，发布日期：2018-11-28，末次修改日期：2024-10-16。实验方法：电子显微镜（分辨率6.88埃）。引用文献：《锌与质子对GluN1/GluN2A型NMDA受体的抑制机制》，《细胞》（Cell），第175卷，2018年。