Shared genetics of blood traits identify clonal hematopoiesis risk loci and a polygenic predictor of leukemia risk

Each data set contains the following four columns: SNP = single nucleotide polymorphism rsID CHR = chrosmome number BP = base pair position in build 37 of the human genome FP = the functional P-value (interpreted like a standard P-value) from the surrogate functional False Discovery Rate (sfFDR) analysis of the UK Biobank genome-wide association summary statistics from Kessler, et al. (https://doi.org/10.1038/s41586-022-05448-9). The overall_inc_ch_bcx_eur_sffdr_res.txt file contains results for the overall clonal hematopoiesis (CH) phenotype. The overall_exc_ch_bcx_eur_sffdr_res.txt file contains results for the overall CH phenotype after excluding individuals carrying mosaic chromosomal alterations.