Electrophysiological defects in a novel patient-derived stem cell model of desmoglein-2 mutant ARVC
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=70c5ebb5bdcb486c9bdf57e4c3b54f78
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资源简介:
Here we developed a novel human induced pluripotent stem cell (hiPSC) model of ARVC to gain insight into the electrical and biomolecular effects of desmoglein-2 (DSG2) mutation in cardiomyocytes. hiPSC-derived cardiomyocytes (hiPSC-CMs) were generated from peripheral blood mononuclear cells donated by an ARVC patient with a pathogenic variant in DSG2, c.2358delA.
提供机构:
Johns Hopkins University
创建时间:
2022-02-20



