Comparison of properties among mutational classes.

110 of the 231 mutants failed to form diploids or showed evidence of contamination and were thus not tested for changes in copy number of the reporter gene. These genotypes showed no changes in the coding sequence, promoter, or terminator of the reporter gene, thus they were either trans-acting or CNVs, but could not be definitively assigned.
2Z-scores were calculated separately for YFP and CFP in haploid and diploid populations using the mean and standard deviation of control populations with the same ploidy. Therefore, the values of Z-scores should not be directly compared between haploid and diploid genotypes or between reporter genes.
3Only the 20 trans-acting mutants not classified as recessive were considered.