We characterize the transcriptomic profile of a set of human IgG1 and IgG4-switched memory B cell clones Overall design: mRNA profiles of human B cell clones were generated by deep sequencing
CT26 tumors were implanted subcutaneously into syngeneic BALB/C mice and allowed to grow for 15-25 days. Tumors were collected, mechanically dissociated, and immune cells enriched using Percoll gradie
Breast cancer cells or tumors underwent RNA-sequencing or single cell RNA-sequencing to study the role of HSF1 in tumor-immune interactions. Overall design: Human MDA-MB-231 and mouse 4T1 cells expres
Temporal analysis of the T cell receptor (TCR) repertoire has been used to monitor treatment-induced changes in antigen-specific T cells in patients with cancer. However, the lack of experimental mode